pain relief (read on)
pain relief (read on)
16th January 2002
GW Expands Phase Three Clinical Trials Programme
of Cannabis-Based Medicine Into Cancer Pain
GW Pharmaceuticals plc, the company developing a portfolio of non-smoked cannabis-based prescription medicines, announces that it has expanded its Phase Three clinical trials programme into cancer pain. This Phase Three trial is the first large-scale trial of its kind and will examine the effectiveness of a cannabis-based medicine in treating pain associated with cancer.
Cancer pain represents the second key target market for GW's programme of developing cannabis-based medicines for a range of medical conditions. The Institute of Medicine in the United States has reported that some of the most encouraging clinical data on the effects of cannabis on chronic pain are from studies of cancer pain .
Over 100 patients, who have terminal cancer and are experiencing pain that is not responding adequately to current therapy, will take part in the double-blind, placebo-controlled study at more than 20 centres around the UK. The cannabis-based medicine is being administered by means of a sublingual (under-the-tongue) spray.
Dr Geoffrey Guy, Executive Chairman of GW, commented, "This is a significant milestone for GW, and - we hope - for sufferers from cancer pain. Cannabis-based medicine has the potential to provide considerable advantages over current medications to cancer patients. The potential market is very significant since approximately 40 per cent of cancer sufferers at present have unmet needs in pain suppression."
The new cancer trial is part of a significant expansion of GW's pivotal regulatory clinical trials programme which will continue throughout the coming months. GW is already conducting a Phase Three trial in Multiple Sclerosis patients. Recruitment for this trial is proceeding on track with 135 patients screened, of which 62 are already enrolled. Up to a further 35 patients may become eligible for entry in the coming weeks.
As part of its clinical trials expansion, GW has commenced further clinical studies including a Phase Three randomised placebo-controlled trial in brachial plexus injury, a severe form of nerve-damage pain. (This injury commonly results from motorcycle accidents and follows a wrenching of the arm and traumatic disruption of nerve connections leading to extreme pain.)
The aim of each of GW's clinical programmes is to prepare data for Product Licence Approval by the Medicines Control Agency. Phase Three of the trials programme is the final stage in preparing for an application to be made for a Product Licence Approval.
New positive data from GW's Phase Two clinical trials in Multiple Sclerosis and Spinal Cord Injury is provided in the preliminary results announced separately today. This encouraging data shows significant improvements in a range of symptoms.
Institute of Medicine, Division of Neuroscience and Behavioral Health, Janet E. Joy, Stanley J. Watson, Jr., and John A. Benson, Jr., "Marijuana and Medicine: Assessing the Science Base"
GW Expands Phase Three Clinical Trials Programme
of Cannabis-Based Medicine Into Cancer Pain
GW Pharmaceuticals plc, the company developing a portfolio of non-smoked cannabis-based prescription medicines, announces that it has expanded its Phase Three clinical trials programme into cancer pain. This Phase Three trial is the first large-scale trial of its kind and will examine the effectiveness of a cannabis-based medicine in treating pain associated with cancer.
Cancer pain represents the second key target market for GW's programme of developing cannabis-based medicines for a range of medical conditions. The Institute of Medicine in the United States has reported that some of the most encouraging clinical data on the effects of cannabis on chronic pain are from studies of cancer pain .
Over 100 patients, who have terminal cancer and are experiencing pain that is not responding adequately to current therapy, will take part in the double-blind, placebo-controlled study at more than 20 centres around the UK. The cannabis-based medicine is being administered by means of a sublingual (under-the-tongue) spray.
Dr Geoffrey Guy, Executive Chairman of GW, commented, "This is a significant milestone for GW, and - we hope - for sufferers from cancer pain. Cannabis-based medicine has the potential to provide considerable advantages over current medications to cancer patients. The potential market is very significant since approximately 40 per cent of cancer sufferers at present have unmet needs in pain suppression."
The new cancer trial is part of a significant expansion of GW's pivotal regulatory clinical trials programme which will continue throughout the coming months. GW is already conducting a Phase Three trial in Multiple Sclerosis patients. Recruitment for this trial is proceeding on track with 135 patients screened, of which 62 are already enrolled. Up to a further 35 patients may become eligible for entry in the coming weeks.
As part of its clinical trials expansion, GW has commenced further clinical studies including a Phase Three randomised placebo-controlled trial in brachial plexus injury, a severe form of nerve-damage pain. (This injury commonly results from motorcycle accidents and follows a wrenching of the arm and traumatic disruption of nerve connections leading to extreme pain.)
The aim of each of GW's clinical programmes is to prepare data for Product Licence Approval by the Medicines Control Agency. Phase Three of the trials programme is the final stage in preparing for an application to be made for a Product Licence Approval.
New positive data from GW's Phase Two clinical trials in Multiple Sclerosis and Spinal Cord Injury is provided in the preliminary results announced separately today. This encouraging data shows significant improvements in a range of symptoms.
Institute of Medicine, Division of Neuroscience and Behavioral Health, Janet E. Joy, Stanley J. Watson, Jr., and John A. Benson, Jr., "Marijuana and Medicine: Assessing the Science Base"
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jennyb
- Posts: 1183
- Joined: Fri Nov 02, 2001 5:24 pm
- Injury Description, Date, extent, surgical intervention etc: January 1980 Yamaha RD200 vs 16 wheeler truck, result, 1 totally paralysed right arm. I was 21, now 54. I had no surgery, I don't regret this. Decided to totally ignore limitations (easily done aged 21) adapted very quickly to one handed life, got married, had 3 kids, worked- the effect of the injury on my life (once the pain stopped being constant) was minimal and now, aged 54, I very rarely even think of it, unless I bash it or it gets cold, then I wish I'd had it amputated :) Except for a steering knob on my car, I have no adaptations to help with life, mainly because I honestly don't think of myself as disabled and the only thing I can't do is peel potatoes, which is definitely a good thing.
Re: pain relief (read on)
so...where do we sign up Hazey???
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George
Re: pain relief (read on)
good to see that "brachial plexus injuries" were mentioned SPECIFICLY with regard to treating chronic & severe pain............finally. Codein should not be the only player in the ring, especially if THC turns out to be lots safer.
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admin
- Site Admin
- Posts: 19873
- Joined: Mon Nov 16, 2009 9:59 pm
Re: pain relief (read on)
Hi there folks. Yeah my pain specialist at stanmore is currently running cannabis trials in chronic pain sufferers. may be on the trial in may. Would be good as i could stop paying for it! tee-hee. xx
Re: pain relief (read on)
george i posted it cos its one of the only times ive read anything & they acknowledge bpi injuries as causing severe pain. i know which one out of codeine & thc causes me the least problems.
jenny mmmmmmm never got as far as how to sign up thats the next move.
bye hazel
jenny mmmmmmm never got as far as how to sign up thats the next move.
bye hazel
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MarcsOnFire
- Posts: 33
- Joined: Sun Nov 04, 2001 1:36 pm
Re: pain relief (read on)
Isn't this the thing that Liz "God Damn I'm Lucky, I Get To Smoke Naughty Stuff....LEGALLY" Black is doing up at Stanmore??? I think it very well might be.
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jennyb
- Posts: 1183
- Joined: Fri Nov 02, 2001 5:24 pm
- Injury Description, Date, extent, surgical intervention etc: January 1980 Yamaha RD200 vs 16 wheeler truck, result, 1 totally paralysed right arm. I was 21, now 54. I had no surgery, I don't regret this. Decided to totally ignore limitations (easily done aged 21) adapted very quickly to one handed life, got married, had 3 kids, worked- the effect of the injury on my life (once the pain stopped being constant) was minimal and now, aged 54, I very rarely even think of it, unless I bash it or it gets cold, then I wish I'd had it amputated :) Except for a steering knob on my car, I have no adaptations to help with life, mainly because I honestly don't think of myself as disabled and the only thing I can't do is peel potatoes, which is definitely a good thing.
Re: pain relief (read on)
why does it say there are 5 replies to this thread? I count 4....is there post removal still happening or what? There's been a post waiting to be added to the 'suggestions box' forum for a couple of days now, but it hasn't appeared....this happened last week too.....and that time it never appeared at all...how many messages contravening the 'guidelines' can you get? seems like a lot......
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karlos
Re: pain relief (read on)
Yehh I noticed this too, a couple of folk replied to Chris (the stuntbike geezer)it said 2 new posts but non came up,even tho the post came to the top of the board.
thought it was the old morphine kicking in again!
karl
thought it was the old morphine kicking in again!
karl
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admin
- Site Admin
- Posts: 19873
- Joined: Mon Nov 16, 2009 9:59 pm
Re: pain relief (read on)
ditto i was wondering that, i just thought i couldnt count:)
or maybe its that cyber monster that kicks us all out of chat lol.
bye hazel
or maybe its that cyber monster that kicks us all out of chat lol.
bye hazel
Re: pain relief (read on)
ditto i was wondering that to, just thought id taken part in the trials & forgot how to count. or is it the chat room cyber monster:)
does anyone have probs with autologin? i have to sign in every time even iif i tick the box. hence there maybe 2 messages from me.
bye hazel
does anyone have probs with autologin? i have to sign in every time even iif i tick the box. hence there maybe 2 messages from me.
bye hazel
