Paralyzed dog walks again after nose cell treatment
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Christopher
- Posts: 845
- Joined: Wed Jun 18, 2003 10:09 pm
- Injury Description, Date, extent, surgical intervention etc: Date of Injury: 12/15/02
Level of Injury:
-dominant side C5, C6, & C7 avulsed. C8 & T1 stretched & crushed
BPI Related Surgeries:
-2 Intercostal nerves grafted to Biceps muscle,
-Free-Gracilis muscle transfer to Biceps Region innervated with 2 Intercostal nerves grafts.
-2 Sural nerves harvested from both Calves for nerve grafting.
-Partial Ulnar nerve grafted to Long Triceps.
-Uninjured C7 Hemi-Contralateral cross-over to Deltoid muscle.
-Wrist flexor tendon transfer to middle, ring, & pinky finger extensors.
Surgical medical facility:
Brachial Plexus Clinic at The Mayo Clinic, Rochester MN
(all surgeries successful)
"Do what you can, with what you have, where you are."
~Theodore Roosevelt - Location: Los Angeles, California USA
Paralyzed dog walks again after nose cell treatment
VIDEO:
http://www.reuters.com/video/2014/04/01 ... =239263241
VIDEO TRANSCRIPT:
UPSOT: 'Come on, Jasper' Ten-year-old dachshund Jasper is rediscovering his hind legs. Four years ago, an accident rendered them useless but now, after ground-breaking treatment, he's up and running again. The keys to Jaspers' recovery, came from his nose. SOUNDBITE (English) MAY HAY, OWNER OF JASPER, SAYING: "They took the stem cells from his nose, but it's done through the skull, so not as straightforward as one might think and that wasn't too bad for him. He coped and then we had him home and then it was about four weeks later that they did the injections." Owners Peter and May Hay agreed to let Jasper join 33 other dogs with similar disabilities in a six month medical trial. Most were treated with olfactory ensheathing cells injected into the injury site. The rest were injected with a placebo. By the end of the trial many of those who received the cells were able to walk again. The research team responsible, led by study co-author Professor Robin Franklin, say the technique could one day help treat humans. SOUNDBITE (English) CO-AUTHOR OF STUDY, PROFESSOR ROBIN FRANKLIN OF CAMBRIDGE UNIVERSITY, SAYING: "Olfactory ensheathing cells are very specialised cells that are found in the part of the nervous system that deals with the special sense of smell, or olfaction, and this is a part of the nervous system that continually regenerates the nerve cells that pick up odours in the environment. They're very vulnerable because they're poking into the environment and if there wasn't a capacity to keep regenerating these nerve fibres we'd lose the sense of smell very quickly." The procedure could eventually be used alongside drug treatments to promote nerve fibre regeneration and help restore some movement in human paraplegics but Professor Geoffrey Raisman, who discovered olfactory ensheathing cells in 1985, says it does not represent a cure for paralysis. SOUNDBITE (English) PROFESSOR GEOFFREY RAISMAN, CHAIR OF NEURAL REGENERATION AT UNIVERSITY COLLEGE LONDON, SAYING: "This kind of response has already been shown in experimental animals. This extends it to another species. The problem is that this is one function, which is the ability of the hind limbs to follow the four limbs. It would not be relevant, for example, to most of the things that affect spinal injured patients like use of the hands or control of the bowel or bladder or sexual function." For Jasper, partial communication has been restored within the spinal cord - an encouraging advance - and Peter Hay is delighted with the results. SOUNDBITE (English) PETER HAY, OWNER OF JASPER, SAYING: "He's just a functioning dog now. He walks with the other dogs, he goes on exactly the same length of walk, he goes into the same ditches, he comes out of them. It's just another dog." The project was a collaboration between the Medical Research Council's Regenerative Medicine Centre and Cambridge University's Veterinary School. Although potential human trials are years away, Jasper's owners say they're grateful for the researchers' dogged determination.
http://www.reuters.com/video/2014/04/01 ... =239263241
VIDEO TRANSCRIPT:
UPSOT: 'Come on, Jasper' Ten-year-old dachshund Jasper is rediscovering his hind legs. Four years ago, an accident rendered them useless but now, after ground-breaking treatment, he's up and running again. The keys to Jaspers' recovery, came from his nose. SOUNDBITE (English) MAY HAY, OWNER OF JASPER, SAYING: "They took the stem cells from his nose, but it's done through the skull, so not as straightforward as one might think and that wasn't too bad for him. He coped and then we had him home and then it was about four weeks later that they did the injections." Owners Peter and May Hay agreed to let Jasper join 33 other dogs with similar disabilities in a six month medical trial. Most were treated with olfactory ensheathing cells injected into the injury site. The rest were injected with a placebo. By the end of the trial many of those who received the cells were able to walk again. The research team responsible, led by study co-author Professor Robin Franklin, say the technique could one day help treat humans. SOUNDBITE (English) CO-AUTHOR OF STUDY, PROFESSOR ROBIN FRANKLIN OF CAMBRIDGE UNIVERSITY, SAYING: "Olfactory ensheathing cells are very specialised cells that are found in the part of the nervous system that deals with the special sense of smell, or olfaction, and this is a part of the nervous system that continually regenerates the nerve cells that pick up odours in the environment. They're very vulnerable because they're poking into the environment and if there wasn't a capacity to keep regenerating these nerve fibres we'd lose the sense of smell very quickly." The procedure could eventually be used alongside drug treatments to promote nerve fibre regeneration and help restore some movement in human paraplegics but Professor Geoffrey Raisman, who discovered olfactory ensheathing cells in 1985, says it does not represent a cure for paralysis. SOUNDBITE (English) PROFESSOR GEOFFREY RAISMAN, CHAIR OF NEURAL REGENERATION AT UNIVERSITY COLLEGE LONDON, SAYING: "This kind of response has already been shown in experimental animals. This extends it to another species. The problem is that this is one function, which is the ability of the hind limbs to follow the four limbs. It would not be relevant, for example, to most of the things that affect spinal injured patients like use of the hands or control of the bowel or bladder or sexual function." For Jasper, partial communication has been restored within the spinal cord - an encouraging advance - and Peter Hay is delighted with the results. SOUNDBITE (English) PETER HAY, OWNER OF JASPER, SAYING: "He's just a functioning dog now. He walks with the other dogs, he goes on exactly the same length of walk, he goes into the same ditches, he comes out of them. It's just another dog." The project was a collaboration between the Medical Research Council's Regenerative Medicine Centre and Cambridge University's Veterinary School. Although potential human trials are years away, Jasper's owners say they're grateful for the researchers' dogged determination.
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ASC
- Posts: 113
- Joined: Mon Oct 08, 2012 10:41 am
- Injury Description, Date, extent, surgical intervention etc: OBPI
Re: Paralyzed dog walks again after nose cell treatment
Interesting and informative!
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ajones
- Posts: 2
- Joined: Sat Mar 01, 2014 6:14 pm
- Injury Description, Date, extent, surgical intervention etc: happend dec 18 2012, while at work i was hit with a telephone pole, which fractured my skull and damaged the c5 c6 c7 c8 t1, all of which were avulsed i believe, c5 c6 c7 for sure, i had one nerve grafting surgery in februrary 2013, and in may i had two nerves taken out of my intercostel, and one from my upper back sown into my left arm, now being march 1st of 2014, i have a little bet of movement in my left shoulder, but that is, all and after seeing my neuro surgeon on the 27 of februrary, i was told that i will never be able to move my left hand again, so after hearing made me want to find another way to cure this, and according to my neuro surgeon there are no other surgeries that can be done to help save my hand, thats why i think use of stem cells or something along those lines are the only way to potentially save my hand.
- Location: vancouver, canada
Re: Paralyzed dog walks again after nose cell treatment
Had they started performing this on people yet? And if no, why not, I would be more than willing to volunteer myself so they could try it on human patients, does anyone know if there's a way I could sign up for testing? Any info would be greatly appreciated, thank you.
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Izka
- Posts: 2
- Joined: Thu Feb 09, 2017 12:36 pm
- Injury Description, Date, extent, surgical intervention etc: BPI of the left arm at birth
Date: 11/21/2012
Re: Paralyzed dog walks again after nose cell treatment
Hi Christopher,
How are you? First, I would like to thank you for the time you spend searching for the useful information and for sharing of them with us.
I have a 4 year old daughter, who has a BPI of the left arm. She was severely injured at birth. She went through 3 surgeries with a minimal success. She has no function of the elbow and shoulder. Now, I am looking for a new neurosurgeon or orthopedic surgeon who could help us. On the internet, I found many names but we need someone highly specialized. You underwent through several surgeries, is there someone who you particularly recommend? Do the surgeries have brought the expected results? I am looking also for the information about the stem cells injection for BPI patients. Do you know whether it is still a metter of research or if someone does it?
Sorry for asking so many questions but I am determined. Plus, I think you have a big knowledge and I hope you can help me. For any information I will be very grateful.
Wishing you the very best of luck!!!!
Magdalena
How are you? First, I would like to thank you for the time you spend searching for the useful information and for sharing of them with us.
I have a 4 year old daughter, who has a BPI of the left arm. She was severely injured at birth. She went through 3 surgeries with a minimal success. She has no function of the elbow and shoulder. Now, I am looking for a new neurosurgeon or orthopedic surgeon who could help us. On the internet, I found many names but we need someone highly specialized. You underwent through several surgeries, is there someone who you particularly recommend? Do the surgeries have brought the expected results? I am looking also for the information about the stem cells injection for BPI patients. Do you know whether it is still a metter of research or if someone does it?
Sorry for asking so many questions but I am determined. Plus, I think you have a big knowledge and I hope you can help me. For any information I will be very grateful.
Wishing you the very best of luck!!!!
Magdalena
